Biological Resource Center, NITE (NBRC)

Mass Spectrometer Introduction

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Using protein analysis technology developed over many years, we are investigating the causes of products that have caused allergic accidents and examining technical standards and evaluation methods for biomolecule-related products in NITE Biological Resource Center (NBRC). The mass spectrometers used for the analysis are introduced below.
Laboratory photo

Mass Spectrometers used for Analysis

The analysis is performed using time-of-flight mass spectrometer (TOF-MS), high performance liquid chromatograph mass spectrometer (LC/MS) and gas chromatograph mass spectrometer (GC/MS).

Time-Of-Flight Mass Spectrometer (TOF-MS)

Matrix-Assisted Laser Desorption Ionization-Time-Of-Flight Mass Spectrometer (MALDI-TOF-MS)

[Model]
Bruker Daltonics: autoflex™ speed

[Application]
Fungi in Air Conditioners
 

Matrix-Assisted Laser Desorption Ionization-Tandem Time-Of-Flight Mass Spectrometer (MALDI-TOF/TOF-MS)

[Model]
Bruker Daltonics: ultraflex TOF/TOF

[Application]
Identification of Cashmere Fibersopen a page in a new window
Proteome Projectsopen a page in a new window (DBRPopen a page in a new window)

High Performance Liquid Chromatograph Mass Spectrometer (LC/MS)

Orbitrap Mass Spectrometer (OT-MS)

[Model]
Thermo Scienitific™:
Orbitrap Exploris 240 /FAIMS Pro Duo (nanoESI)
nano LC (AMR: Zaplous U3000-PAL System)

[Application]
Fungi in Air Conditioners

Linear Ion Trap Mass Spectrometer (LIT-MS)

[Model]
Thermo Scienitific™: LTQ XL™ /ETD (nanoESI)
nano LC (AMR: Zaplous U3000-PAL System)

[Application]
Fungi in Air Conditioners
Identification of Cashmere Fibersopen a page in a new window
Hydrolyzed Wheat Proteins
Proteome Projectsopen a page in a new window (DBRPopen a page in a new window)
 

Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (FT-ICR-MS)

[Model]
Bruker Daltonics: solariX 7T (ESI, APCI, APPI)
UHPLC (JASCO: X-LC™)
HPLC (JASCO: EXTREMA 4000 Model Inert type)
HPLC (Shimadzu: Prominence)

[Application]
Microbial Carotenoidsopen a page in a new window (DBRPopen a page in a new window)
Identification of Cashmere Fibersopen a page in a new window
Azo Dyes
Dermopathy Accidents
Degraded Kerosene
 

Triple Quadrupole Mass Spectrometer (QqQ-MS)

[Model]
Waters™: Quattro Premier XE™ (ESI, APCI)
HPLC (Waters™: 1525 Binary)
semi micro HPLC (JASCO: PU-4185-Binary)

[Application]
Identification of Cashmere Fibersopen a page in a new window
Azo Dyes
Dermopathy Accidents
 

Single Quadrupole Mass Spectrometer (Q-MS)

[Model]
Shimadzu: LCMS-2020 (ESI, APCI)
UHPLC (Shimadzu: Nexera™ XR)

[Application]
Identification of Cashmere Fibersopen a page in a new window
Dermopathy Accidents

[Term]
ESI: Electrospray ionization
APCI: Atmospheric pressure chemical ionization
APPI: Atmospheric pressure photoionization

Gas Chromatograph Mass Spectrometer (GC/MS)

Double Focusing Mass Spectrometer (EB-MS)

[Model]
JEOL: MStation JMS-700 (EI, CI)
GC (Agilent: 8890 GC system)

[Application]
Azo Dyes
Dermopathy Accidents

[Term]
EI: Electron ionization
CI: Chemical ionization

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Analysis Results

Analysis results from mass spectrometers are available to be downloaded from the DBRP (Data and Biological Resource Platformopen a page in a new window).

Contact us

 Biotechnology Evaluation and Development Division,  Biological Resource Center,  National Institute of Technology and Evaluation

Address:2-49-10 Nishihara, Shibuya-ku, Tokyo 1510066, Japan MAPopen a page in a new window
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